Behnam Ranjbar defended his Thesis titledPlatelet-Rich Plasma Eye Drops for the Treatment of Persistent Corneal Epithelial Defects


PRP eye drops were prepared with a specific ratio of autologous platelet-rich plasma aliquoted to sterile multidose vials. 51 patients with persistent corneal epithelial defects were treated with PRP eye drops four times a day. The patients were categorized into post-surgical, post-transplantation, dry eyes, chemical burns and miscellaneous subgroups. Slitlamp biomicroscopic examinations together with photoslit photography were performed at the baseline and weekly until complete healing. Mean duration of treatment between subgroups was analyzed by ANOVA test. Moreover, mean duration of corneal defect before and after initiation of the treatment was compared by paired t-test.

This study was performed to investigate the effects of platelet-rich plasma (PRP) eye drop on the healing of persistent corneal epithelial defects.

Our findings suggest that treatment with autologous PRP eye drops seems to be an effective and reliable approach that accelerates epithelial would healing in cases with persistent corneal epithelial defects of various etiologies.






Supervisors: Sh. Alizade, Associate Professor

A. Baradaran Rafiee, Professor

Advisors: M. Rezaei Canvi, Associate Professor

F. Nadali, Associate Professor

Reviewers: H. Mousavi, Assistant Professor

M. Azad, Assistant Professor